A “clinical trial” is a study in human patients for an emerging therapy that has not been adopted as standard therapy. This website has pages that enable patients to search worldwide for currently recruiting clinical trials with ether cord blood or umbilical cord tissue MSC. The table below checks off all diagnoses that have ever been treated in clinical trials with cord blood or cord tissue, regardless of whether the trials are still open.
Each cord blood bank has different directions for returning the consent form. Some banks may ask you to mail the consent form along with the health history forms or to bring the original consent form with you to the hospital. Other banks may have you finish the form at the hospital. Follow the directions from your public cord blood bank.
If you’re unsure about what you’d like to do, then speak with your doctor about your family’s medical history. Ask if there is a risk to your child that could be minimized with cord blood banking. In doing so, you’ll be able to find the decision which works the best for you.
Many of these conditions require radiation or chemotherapy, which work by killing harmful cells but also kill healthy cells at the same time. Transplanting cord blood stem cells into patients undergoing those cancer treatments can help their bodies produce new blood cells that can in turn improve their health.
To prevent graft-versus-host disease and help ensure engraftment, the stem cells being transfused need to match the cells of the patient completely or to a certain degree (depending on what is being treated). Cord blood taken from a baby’s umbilical cord is always a perfect match for the baby. In addition, immediate family members are more likely to also be a match for the banked cord blood. Siblings have a 25 percent chance of being a perfect match and a 50 percent chance of being a partial match. Parents, who each provide half the markers used in matching, have a 100% chance of being a partial match. Even aunts, uncles, grandparents and other extended family members have a higher probability of being a match and could possibly benefit from the banked cord blood. Read more reasons why you should bank cord blood.
The key benefit of cord blood banking involves those stem cells. Those cells can turn themselves into numerous other cells that can help older children (or even adults) receive a level of protection from a disease, such as leukemia, that attacks the immune or circulatory system. Even certain metabolic disorders can be treated thanks to stem cells saved through cord blood banking.
Why should you consider donating the cord blood to a public bank? Simply because, besides bringing a new life into the world, you could be saving an individual whose best chance at life is a stem cell transplant with your baby’s donated cord blood. This can only happen if you donate and if your baby is a close enough match for a patient in need. If you chose to reserve the cord blood for your family, then siblings who have the same parents have a 25% chance of being an exact match.
Parents who wish to donate cord blood are limited by whether there is a public bank that collects donations from the hospital or clinic where their baby will be born. Search our list of public banks in your country. Parents who wish to store cord blood and/or cord tissue for their family can find and compare private banks in your country. Family banks usually offer payment plans or insurance policies to lower the cost of cord blood banking.
Now that you know the cord blood banking pros and cons, there really isn’t a right or wrong thing to do. The question is simply – What’s right for your family? Reputable websites and testimonials are your saving grace if you’re on the fence for investing or even donating.
To save money, public banks will not even process a cord blood donation unless they know in advance that they are going to keep it. When the collection first arrives at the lab, it is passed through a cell counting machine. Only collections that have at least 900 million nucleated cells are kept. As a result, over 60%-80% of cord blood donations are discarded. The public bank must absorb the expense of the collection kit and delivery charges for discarded blood; typically $100 per unit.
The Medical Letter On Drugs and Therapeutics also recently addressed aspects of public and private cord blood banks, asking the question: “Does Private Banking Make Sense?” After citing various statistics on the actual uses of privately stored cord blood, they concluded that: “At the present time, private storage of umbilical cord blood is unlikely to be worthwhile. Parents should be encouraged to contribute, when they can, to public cord blood banks instead.” [Access The Medical Letter at www.medicalletter.org].
Cord blood is collected by your obstetrician or the staff at the hospital where you give birth. Not all hospitals offer this service. Some charge a separate fee that may or may not be covered by insurance.
In an allogenic transplant, another person’s stem cells are used to treat a child’s disease. This kind of transplant is more likely to be done than an autologous transplant. In an allogenic transplant, the donor can be a relative or be unrelated to the child. For an allogenic transplant to work, there has to be a good match between donor and recipient. A donor is a good match when certain things about his or her cells and the recipient’s cells are alike. If the match is not good, the recipient’s immune system may reject the donated cells. If the cells are rejected, the transplant does not work.
This is a huge risk and must be definitely thought out before making the decision. Leaving the umbilical cord on for 1 minute is proven to increase hemoglobin levels and improves iron levels in the first several months of life. This aids tremendously in the transition for your little one to breathe.
You’ve just visited the doctor and the good news is that you’re going to have a baby and everything looks good. Thirty years ago, your doctor may have given you a baby book and information about products that sponsors want you to buy for your new addition. Today, along with pretty much the same materials, you’ll be asked to consider saving the blood of your newborn that’s left over in the umbilical cord and placenta after the delivery. Another big decision, and possibly a costly one.
“It’s critically important for patients to get balanced information and answers to their questions about cord blood banking. Because there are so many companies advertising their services, it can be difficult to understand information on the internet.”
The Leading the Way LifeSaving Ambassadors Club is a recognition program honoring sponsor groups for outstanding performance in reaching or exceeding blood drive collections goals. CBC presents a Leading the Way plaque to winning sponsors on an annual basis. The award is based on three levels of achievement:
If you are considering donating your child’s cord blood, or if you have questions or concerns, call the St. Louis Cord Blood Bank at 314-268-2787 or 888-453-2673 to register. A nurse is available to answer your questions between the hours of 7 am – 5 pm Monday through Friday. See more about the donation process here »
Chloe Savannah Metz’ mother donated her baby girl’s cord blood to the NCBP in December 2000. “Many thanks to the New York Blood Center for giving us the opportunity to donate our cord — we hope to give someone a second chance!” – Christine Metz
Genes: Segments of DNA that contain instructions for the development of a person’s physical traits and control of the processes in the body. They are the basic units of heredity and can be passed down from parent to offspring.
Cord blood banking has become more popular over the last few years. And at some point or another, you may have noticed information about it at your doctor’s office. But what is it, exactly — and is it something you should do?
If you pay a private bank to store your cord blood, then it will always be available to you. No one can access the cord blood unless you authorize it. It will be reserved for your family and no one else. It cannot be donated for research purposes if your account remains in good standing. There may not be a guarantee that you’ll ever use it, but at least you’ll have it should there be a need to use it in the future.
FAQ172: Designed as an aid to patients, this document sets forth current information and opinions related to women’s health. The information does not dictate an exclusive course of treatment or procedure to be followed and should not be construed as excluding other acceptable methods of practice. Variations, taking into account the needs of the individual patient, resources, and limitations unique to the institution or type of practice, may be appropriate.
There are around 30 private banks in the U.S. too. If you decide to opt for private storage, you should choose a cord blood bank that’s registered with the Food and Drug Administration (FDA) and accredited by the American Association of Blood Banks (AABB). AABB accreditation is the gold standard in cord blood banking, ensuring that your baby’s cord blood is collected, stored, processed and distributed safely and effectively.
The parents who make the decision to store their baby’s cord blood and cord tissue are thinking ahead, wanting to do right from the start (even before the start), and taking steps to do whatever they can to protect their baby down the road. Today, many conscientious parents are also considering delayed cord clamping (DCC), a practice in which the umbilical cord is not clamped immediately but rather after it continues to pulse for an average of 30 seconds to 180 seconds. Many parents don’t realize that they can delay the clamping of the cord and still bank their baby’s cord blood. As noted early, our premium processing method, PrepaCyte-CB, is able to capture more immune system cells and reduce the greatest number of red blood cell contaminants. This makes it go hand in hand with delayed cord clamping because it is not as affected by volume, effectively making up for the smaller quantity with a superior quality. You can read more about delayed cord clamping vs. cord blood banking here.
‡ Payment Plan Disclosures for in-house CBR 6-Month Plan (interest free) – No credit check required. The 6-month plan requires a $10/month administrative fee. The plans may be prepaid in full at any time.
Since then, many families who suffered from a compatible disease grew hopeful for this newfound anecdote that seems to save so many lives effortlessly. This year to count there are 600,000 umbilical cord blood samples that have been stored and over 30,000 transplants performed. Cord blood can save lives, but cord blood banking may not be the right decision for you and your family. Read on to find out why.
This web page was researched by Frances Verter, PhD, Alexey Bersenev, MD PhD, and Pedro Silva Couto, MSc ©2016-2018. Sources of information about established therapies were publications in the medical literature found via PubMed and Google Scholar. Sources of clinical trials were searches of ClinicalTrials.gov, Chinese Clinical Trial Registry (ChiCTR), Japan University hospital Medical Information Network Clinical Trial Registry (UMIN-CTR), Japan Medical Association Clinical Trial Registry (JMA-CTR), Clinical Research Information Service from South Korea (CRiS), EU Clinical Trials Register (EudraCT), World Health Organization International Clinical Trials Registry Platform (ICTRP), Netherlands Trial Register (NTR), Australian New Zealand Clinical Trial Registry (ANZCTR), Clinical Trials Registry-India (CTRI), German Clinical Trials Register (DRKS), and Iranian Registry of Clinical Trials (IRCT).
The next step at either a public or family bank is to process the cord blood to separate the blood component holding stem cells. The final product has a volume of 25 milliliters and includes a cryoprotectant which prevents the cells from bursting when frozen. Typical cost, $250 to $300 per unit.
“This is a medical service that has to be done when your baby’s cells arrive and you certainly want them to be handled by good equipment and good technicians,” says Frances Verter, Ph.D., founder and director of Parent’s Guide to Cord Blood Foundation, a nonprofit dedicated to educating parents about cord blood donation and cord blood therapists. “It’s just not going to be cheap.” Although the American Academy of Pediatrics (AAP) states cord blood has been used to treat certain diseases successfully, there isn’t strong evidence to support cord blood banking. If a family does choose to bank cord blood, the AAP recommends public cord blood banking (instead of private) to reduce costs.
Sometimes, not enough cord blood can be collected. This problem can occur if the baby is preterm or if it is decided to delay clamping of the umbilical cord. It also can happen for no apparent reason. If an emergency occurs during delivery, priority is given to caring for you and your baby over collecting cord blood.
During pregnancy, the placenta and blood within it serve as the lifeline of nourishment from mother to baby through the umbilical cord. Following the birth, these items are usually discarded. However, cord blood is a rich source of adult stem cells, similar to those found in bone marrow. These blood-forming stem cells create all of a person’s blood cells: red cells that carry oxygen, white cells that fight disease, and platelets that help blood clot. It is because of this multipurpose functionality that cord blood is capable of treating more than 80 different diseases, and has saved thousands of lives.
The long-term effects of delayed cord clamping protect your baby from jaundice and iron deficiency anemia well into adolescence. Iron deficiency can result in lower immunity, lower intelligence, and poor gross motor development.
The first cord blood banks were private cord blood banks. In fact, Cryo-Cell is the world’s first private cord blood bank. It wasn’t until later that the government realized the need to preserve cord blood for research and public welfare. As a result, 31 states have adopted a law or have a piece of pending legislation that requires or encourages OBGYNs to educate expectant parents about cord blood banking and many states now have publicly held cord blood banks. As a result, parents have the option of banking their baby’s cord blood privately for the exclusive use of the child and the rest of the family or donating the cord blood to a public bank so that it can be used in research or by any patient who is a match and in need.
The collection of cord blood takes place after the baby has been delivered, so there is no risk to either the mother or baby. The delivery process is not changed or modified because of the cord blood collection. The umbilical cord is clamped, cut and separated from the baby. The baby is then placed in the mother’s arms or taken to a warmer. Only then will your physician or midwife collect the cord blood. The blood from the umbilical cord drains into a standard blood donor collection bag by gravity.
We offer standard and premium cord blood processing options. Our standard service has been used in thousands of successful transplants since 1988 and begins at $1600. For $350 more, our premium service uses a superior new processing method that greatly enhances parents’ return on investment. (Please visit our processing technology page to learn about our cord blood processing methods.) For an additional $950, you can also store your baby’s cord tissue, which has the potential to help heal the body in different ways than cord blood.
After your baby is born, the umbilical cord and placenta are usually thrown away. Because you are choosing to donate, the blood left in the umbilical cord and placenta will be collected and tested. Cord blood that meets standards for transplant will be stored at the public cord blood bank until needed by a patient. (It is not saved for your family.)
We have 12- and 24-month in-house payment plans to spread the initial cost out over time. They require no credit check and begin with little money down. Starting at approximately $2.50 a day, you can help safeguard your baby’s future. After the term of the payment plan, you are then only responsible for the annual storage fee, which begins at $150.
The European Group on Ethics in Science and New Technologies (EGE) has also adopted a position on the ethical aspects of umbilical cord blood banking. The EGE is of the opinion that “support for public cord blood banks for allogeneic transplantations should be increased and long term functioning should be assured.” They further stated that “the legitimacy of commercial cord blood banks for autologous use should be questioned as they sell a service which has presently no real use regarding therapeutic options.”
Cord blood collection happens immediately after delivery. After cutting and clamping the umbilical cord, the doctor or a hospital staff member will use a needle to draw blood from the umbilical cord vein. The blood is collected in a bag and sent off for processing, freezing and storage.
The St. Louis Cord Blood Bank does not participate in any activities that are designed to promote human cloning or the creation of human embryos for the specific purpose of producing embryonic stem cells for research.
The decision to bank your child’s cord blood is a personal one. Some parents believe the potential benefits are too few to justify the cost, or lose the advantages of delayed cord clamping; others believe it’s a worthwhile investment.
Donating cord blood to a public bank adds to the supply and can potentially help others. Donating to a public bank is especially important for ethnic minorities, who are not well represented in cord blood banks. Public cord blood donation increases the chance of all groups finding a match.
Cord blood contains all the same components as normal blood, including red blood cells, white blood cells, platelets and plasma. What makes it special is that it’s also rich in hematopoietic stem cells — special blood-forming stem cells that are similar to those found in bone marrow. These cells can be used to treat many types of diseases.
Prices subject to change until they are paid. Fees apply to single-birth, U.S. customers only. Cancellation fees may apply. All major credit cards accepted. Payment plans cover first-year fees only; future annual storage fees are not included. If not paying by credit/debit card, total first year fees are due at the time of enrollment.
Our annual storage fee is due every year on the birth date of the child and covers the cost of storage until the following birthday. The fee is the same $150 for both our standard and our premium cord blood services. The annual cord tissue storage fee is an additional $150.
In order to preserve more types and quantity of umbilical cord stem cells and to maximize possible future health options, Cryo-Cell’s umbilical cord tissue service provides expectant families with the opportunity to cryogenically store their newborn’s umbilical cord tissue cells contained within substantially intact cord tissue. Should umbilical cord tissue cells be considered for potential utilization in a future therapeutic application, further laboratory processing may be necessary. Regarding umbilical cord tissue, all private blood banks’ activities for New York State residents are limited to collection, processing, and long-term storage of umbilical cord tissue stem cells. The possession of a New York State license for such collection, processing and long-term storage does not indicate approval or endorsement of possible future uses or future suitability of these cells.
Stem cells are able to transform into other types of cells in the body to create new growth and development. They are also the building blocks of the immune system. The transformation of these cells provides doctors with a way to treat leukemia and some inherited health disorders.
If you can afford the costs of cord blood banking, then it makes sense to have it done to protect against the “what ifs” of life. If you cannot, you can still potentially help someone in need by making a donation to a public cord blood bank, which is often free and may just have a small collection fee from the hospital. The world of medicine is changing, which is why cord blood banking is so important. Talk to your doctor today to see if it is something you should be doing!